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In contrast, La2O3 acts as both an inducer of inflammasome assembly as well as an inhibitor of autophagosome fusion as a result of severe and unique injury to the lysosome resulting from phosphate complexation.
Large burns over greater than one-third of the total body surface area (TBSA) result in a massive inflammatory response, which in turn causes severe and unique hemodynamic and cardiovascular challenges.
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Past studies utilizing Salmonella and two distinct genetic populations illustrated differences in gene expression patterns between mild and severe pathologies unique to a genetic background [ 37], demonstrating the importance of assessing responses in lines of interest, such as a commercial line used in this study, for potential application.
Just in the last year, something truly promising has appeared on the horizon for her and other children with severe and debilitating seizure disorders: a unique strain of marijuana that has been found to dramatically reduce life-threatening symptoms that often include hundreds of violent seizures a day.
But China's pollution, while extremely severe, is not unique, and efforts by other countries, like Britain and the United States, to conquer dirty air may hold lessons for China's future.
True mass casualty events are a very different situation, and by definition they involve such large numbers of victims, or such severe or unique injuries that local medical resources cannot fully cope with them.
Given the complexity and heterogeneity of severe sepsis, and the unique genetically derived susceptibilities of individuals, it is highly unlikely that one or even a handful of biomarkers will provide adequate biomedical information for clinical guidance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com