Sentence examples for severe alignment from inspiring English sources

Moreover, the coating saved us the severe alignment difficulties that were a problem in PDE based conventional etalon modulators.

In agreement with our previous studies [12], addition of 23dMB-PP1 to HCT-Mps1as cells caused severe alignment problems in ∼70% of cells.

High levels of within-cluster heterogeneity among sequences can lead to severe alignment problems [ 72].

For dogs with moderate to severe alignment issues, it will likely not be enough.

Taken together, these data suggest that Cdc5L knockdown causes severe chromosome alignment defects and mitotic arrest.

In addition, mutants in either mamK or mamJ have no magnetite crystallization defect but display severe magnetosome alignment perturbations.

The severe chromosome alignment defects and mitotic cell death observed upon Cdc5L knockdown are distinct from the results of SON knockdown or SKIP knockdown.

Gaitanos et al further demonstrated that a more complete depletion of the Ska complex from HeLa cells, achieved by targeting multiple Ska complex components through RNAi, resulted in severe chromosome alignment defects, stemming from an inability to form stable kinetochore microtubule attachments.

RNAi-resistant GFP-CENP-Mwt localized to kinetochores and rescued the severe chromosome alignment defect caused by the depletion of endogenous CENP-M by RNAi, as well as kinetochore localization of CENP-I, demonstrating the specificity of the RNAi-based depletion of CENP-M.

Severe mis-alignments and bite issues often require "heavier" appliances.

In contrast, in the fulvestrant resistant cell lines, barasertib had a severe effect on chromosome alignment and segregation, and no dividing sister chromatids could be observed.