Asplenic patients are at risk for severe infections, but adherence to recommended preventive education and vaccination is poor.
The fnr mutant of E. coli results in severe defects in adherence to and the invasion of bladder and kidney epithelial cells and was highly attenuated in a mouse model of urinary tract infections (Barbieri et al. 2014).
As the disease progresses, motor and non-motor complications become more severe, making patients' adherence to medication even more important.
The better adherence found in patients who took both aspirin and statin treatment may reflect disease severity, i.e. patients who had more severe conditions had better adherence to medication than those who had less severe conditions.
Despite these relatively high frequencies of severe toxicity per patient, adherence to the protocol-stipulated treatment delays and dose reductions resulted in low rates of severe toxicity per chemotherapy cycle.
Since its launch, the company has raised $7 million in funding from the National Institute of Health, which recognizes how severe the problem of adherence to treatments can be and seems to see promise in the AiCure portfolio of 12 awarded patents.
Although not statistically significant, these results show a consistent trend towards higher levels of adhesion to CD36 in parasites isolated from children with uncomplicated malaria than from children with severe malaria, suggesting that adherence to CD36 might be an indicator of a less pathogenic infection.
10, 11 Lack of availability of testing for glucose-6-phosphate dehydrogenase, concerns over the potential for severe hemolysis, and poor adherence to long courses conspire to prevent widespread use.
The multivariate regression analysis showed that patients with more severe deformity had higher adherence to prescribed footwear maybe because these patients have no other choice than to wear custom-made footwear or because they are more aware of its benefits.
Regarding adherence to the severe sepsis bundles [13], only one PICU reported compliance to all the components of the first severe sepsis bundle (sepsis resuscitation bundle) and three PICUs reported compliance to all elements of the second severe sepsis bundle (sepsis management bundle).
