Sentence examples for severe activation of from inspiring English sources
However, when too severe, activation of ER stress would eventually lead to eukaryotic cell apoptosis [ 53].
Most textbooks state that severe activation of coagulation or DIC is most commonly associated with infection with Gram-negative bacteria.
Despite lung-protective ventilation, abnormalities in plasma levels of markers of inflammation, coagulation and fibrinolysis predict mortality in ALI/ARDS patients, indicating more severe activation of these biologic pathways in nonsurvivors.
Despite lung-protective ventilation, abnormalities in plasma levels of markers of inflammation, coagulation and fibrinolysis predict mortality in ALI patients, indicating more severe activation of these biologic pathways in nonsurvivors.
That exhausted regulation really exists is substantiated by the fact that patients on ICUs with severe activation of the stress system sometimes suffer from lifelong adrenal insufficiency even after overall recovery [ 77].
During severe sepsis, activation of the inflammatory cascade leads to cell damage and organ failure.
If stress is severe, the activation of p53 transcriptional targets such as Bax, Puma and Noxa induces apoptosis.
Although SOCS1 KO mice are normal at birth, they exhibit stunted growth and die within 3 weeks with a syndrome characterized by severe lymphopenia, activation of peripheral T cells, fatty degeneration and necrosis of the liver, and macrophage infiltration of major organs (acute SOCS1-/ disease) [ 36, 37].
Severe injury with activation of the systemic inflammatory response syndrome stimulates the release of cortisol from the adrenal cortex.
Moreover, more studies need to be conducted on the role of RAGE in critical organ derangements involved in the pathogenesis of severe infection, including activation of the coagulation system and the complement system.
The size of the myofibers was significantly smaller and the endomysial fibrosis was significantly higher in the subgroup with severe phenotypes, suggesting that activation of additional signaling pathways leads to more severe phenotypes.
