Sentence examples for severe abnormalities in from inspiring English sources

The vertebrate Hsd17β4 enzyme (also called MFE-2, MFP-2, and DBP) is involved in peroxisomal fatty acid β-oxidation and its deficiency causes severe abnormalities in several organs, particularly in the brain (reviewed in Huyghe et al. 2006).

In humans, null mutations in the LTBP4 gene cause autosomal recessive cutis laxa type 1C (ARCL1C; initially called Urban-Rifkin-Davis syndrome), whish is a rare congenital connective tissue disorder characterized by severe craniofacial anomalies, lax skin and severe abnormalities in several visceral organs including the lung.

Lung disease can lead to severe abnormalities in blood gas composition.

A Roman Catholic, Ms. Gray believed that life began at fertilization, and that abortion was murder and not acceptable for any reason: not for rape or incest, for severe abnormalities in the fetus or to save the woman's life.

Folate deficiency causes severe abnormalities in one-carbon metabolism can result chronic diseases and developmental disorders, including neural tube defects.

In the lungs, the fibrotic process often leads to rapid and severe abnormalities in respiratory mechanics and gas exchange properties.

The aim of the tool was to detect moderate to severe abnormality in the outcomes measured.

Specimens with no sign of previous surgery or any other severe abnormality in the regions of interest were accepted.

The following exclusion criteria were also applied: presence of any symptom indicating serious or malignant disease, drug or alcohol abuse and severe abnormality in the electrocardiogram at rest or the clinical or laboratory examination during the baseline period.

Moreover, we observed more-severe abnormalities in the organization of both cortical MTs and F-actin in rigor-KCBP trichomes when compared to the wild-type control.

Severe abnormalities occurred in 2 patients (10%) treated with single-agent plitidepsin and 4 (11%) treated with plitidepsin/DTIC.