Sentence examples for several types of mutations from inspiring English sources

These studies found that for several types of mutations, one of the most represented was the −1 deletion in a monomeric SSR of five Gs G5-SSR4266) located at position 426 from the mucA start codon (widely known as mucA22 allele) [11], [16], [19] [22].

We demonstrate that this strategy can detect several types of mutations including intronic and exonic changes as well as small indel and a large deletion.

Loss of heterozygosity and several types of mutations in tumour suppressor genes are reported to be involved in cancer development (Feitelson et al, 2002).

Several types of mutations were implicated, many of which affect amino acids within the a determinant region of the S gene; however, our results show that the majority (94.3 %) of mutations occurred outside the major hydrophilic region.

breseq predicts and annotates several types of mutations that produce structural variation by considering new junction (JC) and missing coverage (MC) evidence together with reference sequence annotations of the locations of mobile elements.

We identify several types of derived mutations: SNPs unique to lab strains and SNPs significantly differentiated between lab stains and the wild.

1 Several types of LDL receptor mutation have been described, including premature stop codons, single amino acid substitutions, large rearrangements, mutations affecting the promoter region, and mutations affecting splicing of premessenger RNA.

Interestingly, several types of human tumors contain mutations in the IDH1 gene.

For several types of cancer, certain (secondary) mutations in the EGFR kinase domain have been reported that confer resistance to TKI [ 53– 53].

There are several types of mice with spontaneous mutations or targeted disruptions of genes related to the GH/IGF-1 (somatotropic axis), including the growth hormone receptor/binding protein knock out (GHRKO) mouse, that have extended longevity (Bartke, 2005).

RB1 (the gene coding for the retinoblastoma protein) has been found mutated in several types of cancer [ 2– 5], and germline mutations in the RB1 gene lead to retinoblastomas, in general diagnosed within the first year of life [ 6].