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Real time PCR of the hippocampus confirmed that several transcripts in the CRFergic, serotonergic, and neural plasticity pathways were unaffected by prenatal exposures.
Noticeably, HDL per se diminished the levels of several transcripts in "resting" monocytes including CCL3 and CCL4 (Figure 5), thus correlating results of Table S3.
Upregulation of several transcripts in this cascade was also confirmed by qRT-PCR.
Several transcripts in the network are family members of genes associated with MS (Supplementary Material, Table S8).
In contrast, several transcripts in the TCA cycle are transcriptionally increased in response hypoxia in A. nidulans [ 23].
As previously stated, several transcripts in the terpenoid (isoprenoid) backbone biosynthesis pathway are reduced in response to hypoxia.
Similar(47)
In addition, several transcripts involved in gene regulation, transcription factors, the cytoskeleton and metabolism were analyzed (elongation factor 1 beta, transcription factor AP-1, actin, NADH4).
These clusters contain elements involved in cellular communication and signal transduction and several transcripts involved in glycolysis/glycogenolysis and in the tricarboxylic acid cycle.
In accordance with this observation, SMILE silencing in HeLa cells correlated with the modulation of several transcripts involved in proteolysis and a decrease in proteasome activity.
In support of this model, we detected several transcripts involved in the production of A. apis hydrolytic enzymes, listed in Additional file 1: Table S1.
This was unexpected because in the PNPase deletion mutant several transcripts implied in biofilm formation, like Antigen-43 and the small RNAs omrA and omrB [ 39, 47] were affected (Additional file 1: Table S3).
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