Procalcitonin (PCT), the 116-amino acid precursor of calcitonin, is elevated consecutively in several systemic inflammatory conditions and its magnitude correlates well with injury severity and prognosis [ 7, 8].
As a consequence, several systemic diseases, including autoimmune disorders, originate from the altered balance/activation of the NEI system.
Several systemic effects have been described after talc pleurodesis.
Rheumatic diseases usually promote several systemic disorders, which can affect blood vessels, mucosa and serosa of the aerodigestive tract.
Farmers, milkers and their close contacts developed lesions on the hands, forearms, legs and face accompanied by several systemic symptoms.
In addition, increased prolactin secretion may be caused by prolactin-producing pituitary tumours, such as lactotroph adenomas or prolactinomas, and by several systemic diseases, notably thyroid deficiency.
These mice also showed several systemic autoimmune phenotypes with age, including increased serum levels of anti-dsDNA antibody (Fig. 4c), infiltration of immune cells into tissues (Fig. 4d) and glomerulonephritis (Fig. 4e).
The eating disorders anorexia and bulimia nervosa can cause several systemic and oral alterations related to poor nutrition and induced vomiting; however, the oral microflora of these patients is poorly studied.
There are several systemic biomarkers that could be related to OIIRR.
AKI results from several systemic aggressors such as sepsis, shock, nephrotoxic drugs and major surgery.
When this becomes chronic, several systemic or topical decongestants are available, but all have undesired side effects.
