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It is well known that single eukaryotic genes can give rise to proteins that are localized to several subcellular localizations, an event referred to as dual targeting, dual localization, or dual distribution.
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All nine proteins were predicted to be type II Golgi localized integral membrane proteins by several subcellular localization prediction programs (TargetP, http://www.cbs.dtu.dk/services/TargetP/ and Golgi Predictor, http://ccb.imb.uq.edu.au/golgi/) [ 25], Additional file 1: Table S2).
Several subcellular localization programs, such as TargetP [2] are available that predict these cTPs, with the number of predicted chloroplast (plastid) proteins ranging from about 1500 to 4500 proteins [3], [4].
In this example, the user has opted to search for Genes based on the presence of Transmembrane (TM) domains (one of several subcellular localization queries), and the appropriate search form now appears in the Add Step dialog box.
The possibility to label several proteins with different fluorescent proteins is a great advantage when analyzing their respective subcellular localization.
This context has several aspects –subcellular localization or expression patterns will determine whether proteins that are potential competitors for an interaction in vitro actually meet in vivo and thus evolve into niches of molecular recognition that allow them to bind only the desired target domain.
We were able to assign subcellular localizations to several previously uncharacterized hypothetical proteins, thus improving L interrogans genome annotation.
Several genes were chosen to determine their subcellular localizations and functions.
The differential expression and the multiple subcellular localizations of TCTEX1D4 in testicular cells may indicate that TCTEX1D4 has several functions.
Despite their genetic redundancy, Caulobacter glycosyltransferases exhibit different subcellular localizations.
Thus, the different subcellular localizations of cFLIP may be important for its actions152.
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