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These included increased steady-state levels of genes encoding endogenous BnDGAT1, enzymes of the Kennedy pathway and other lipid-related processes, suggesting that altering DGAT1 levels affects several steps upstream in the fatty acid and TAG biosynthetic pathways.
The discrepancy between αMHC promoter activity and protein expression (αMHC at the protein level was expressed in only a subset of GFP+ cardioblasts) can be rationalized by the fact that promoter activity is several steps upstream of protein synthesis, one of several factors underlying the poor correlation between mRNA and corresponding cellular protein abundance (Vogel & Marcotte, 2012).
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For example x0 may represent an entire G-protein-coupled receptor complex and several other steps upstream of a shared cascade x1.
A few steps upstream.
He plots several steps ahead.
"This takes several steps out.
Take several steps back.
An iron bridge over the Ottauquechee River marks the property's edge; a swimming hole is steps upstream.
Daguerreotypes are made in several steps.
Navigating by magnetism includes several steps.
He plans several steps ahead".
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