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The human serine/threonine-protein phosphatase also exists in several splicing variants.
The inhibition by charybdotoxin of A-type potassium channels expressed in Xenopus oocytes was studied for several splicing variants of the Drosophila Shaker gene and for several site-directed mutants of this channel.
Interferon (IFN) regulatory factor 7 (IRF-7) has several splicing variants, and at least the major splicing variant (IRF-7A) has oncogenic potential and is associated with EBV transformation processes.
In addition, ADSS has several splicing variants.
Furthermore, the expression measured could also be the sum of the expression of several splicing variants.
Our data suggest that current gene and transcript data may still be rather incomplete - with several splicing variants still unknown.
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If several splice variants were present for one protein, we excluded all but the longest transcript.
We are interested in studying the cell and tissue expression of the GST A3-3 gene, yet the existence of highly expressed sequence-similar homologs and of several splice variants is a serious challenge for the specific detection of unique transcript species.
Although several splice variants of EZH2 have been identified, little is known about how EZH2 splicing is regulated or the contribution of alternative splicing to its protumorigenic functions.Experimental Design: We conducted RT-PCR, Western blot analysis, and IHC techniques to examine EZH2 and its alternative splicing transcript expression in renal cancer tissue and renal cancer cell lines.
Formin 1 consists of several splice variants that are differentially expressed in mammalian tissues [23] [26].
Previous studies have demonstrated several splice variants of NET, differing in expression and function [6].
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