Sentence examples for several splice from inspiring English sources

If several splice variants were present for one protein, we excluded all but the longest transcript.

We are interested in studying the cell and tissue expression of the GST A3-3 gene, yet the existence of highly expressed sequence-similar homologs and of several splice variants is a serious challenge for the specific detection of unique transcript species.

Although several splice variants of EZH2 have been identified, little is known about how EZH2 splicing is regulated or the contribution of alternative splicing to its protumorigenic functions.Experimental Design: We conducted RT-PCR, Western blot analysis, and IHC techniques to examine EZH2 and its alternative splicing transcript expression in renal cancer tissue and renal cancer cell lines.

In contrast, in the ob2J strain, the insertion of a retroviral-like transposon featuring several splice acceptor and polyadenylation sites into the first intron of the leptin gene results in the generation of chimeric transcripts and consequently no leptin protein synthesis at all [10],[29].

Previous studies have demonstrated several splice variants of NET, differing in expression and function [6].

Formin 1 consists of several splice variants that are differentially expressed in mammalian tissues [23] [26].

However, many of them present several splice variants, which are designated by a nomenclature in which a variant of SEPT6, for example, would be indicated as SEPT6_v1.

The LDL receptor (LDLR), which is primarily responsible for cellular uptake of LDL from plasma, has several splice variants, the two most common of which involve exon skipping: LDLR4 and LDLR12, respectively.

HNT is known to have several splice isoforms.

90 Several splice variants for sgk3 have also been identified.

Many genes exhibit alternative splicing, with several splice variants created from a single locus.