Sentence examples for several somatic mutations from inspiring English sources

Ding and his colleagues have identified several somatic mutations of Ephs especially EphA7 in lung cancer [ 34].

Many studies assessed the potential prognostic impact of several somatic mutations including KRAS, BRAF, and TP53 mutations after curative surgery 34– 34.

We confirm several somatic mutations from previous studies and expand the known genetic signature of SMZL by several newly discovered mutations.

Recently, several somatic mutations in the EGFR gene have been linked with favourable response to treatment with anti-EGFR tyrosine kinase inhibitors (TKIs), gefitinib and erlotinib, in non-small cell lung cancer (NSCLC) patients (Scaltriti and Baselga, 2006).

In whole-genome sequencing, somatic mutations (e.g., single nucleotide polymorphisms or insertion-deletion mutations) are identified by sequencing the entire genome, and this approach has been used to identify several somatic mutations in various cancers [ 4, 5].

Characterization of CKIε in breast cancer has identified several somatic mutations in the 5′-coding 5′-coding the gene, which could lead to imaginal disc overegionh in Drofophila (Dolezal ethel, 2010; Foldynova-Trantirkova et al, 2010; Fuja et al, 2004).

Several identified somatic mutations occur in genes involved in many signaling, regulatory and metabolic pathways.

But even for cancer treatment assignment, only several hundred somatic mutations are currently viewed as actionable [ 15, 16].

This was evident in the detection of several additional somatic mutations by the Ion Proton (409-gene panel) in comparison to IT-PGM (46-gene panel).

Several novel somatic mutations, such as SF3B1, IDH1, IDH2, DNMT3A, MYD88 and MLL2 have been identified as a consequence of NGS efforts, leading to the discovery of previously unrecognized genes and molecular processes/pathways with pathogenic effects.

Twenty NSCLC samples were analyzed using the arrays, and several well-characterized somatic mutations and germline variants were found.