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Based these results, we suggest that choosing a correct residue for mutation in multi subunit proteins results in multiple site conversions which equals to several simultaneous mutations.
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This would imply that the loss of the primary host and the shift of the entire cycle to a new secondary herbaceous host requires an escape from both these constraints, entailing several major, simultaneous mutations [ 19].
Simultaneous mutations in one of several kinetochore and cohesion genes and a spindle checkpoint gene cause a synthetic-lethal or synthetic-sick phenotype.
Simultaneous mutations in one of several kinetochore and cohesion genes, such as CTF19 and CTF8, and a spindle checkpoint gene cause a synthetic-lethal or synthetic-sick phenotype [29] [31].
In several cases, our data are also consistent with two other paradigms: simultaneous mutations, or a deleterious mutation followed by a compensatory change.
Entrelacement, a literary technique in which several simultaneous stories are interlaced in one larger narrative.
Right now, most of our cities would be as hard-pressed as Mumbai was to deal with several simultaneous attacks.
Managing resources is challenging when there are several simultaneous projects.
Creation of this new ligand activity required the presence of four simultaneous mutations.
At each round, the auction designer announces several simultaneous auctions.
You don't get scared at B-movies or by several simultaneous deadlines.
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