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Changing from a defined medium to a complex medium led to several significant changes in the physiology of all strains, e.g. increased maximum growth rate, increased biomass yield and reduced by-product yields (Additional file 2: Table S3 and Table S4).
Then, several significant changes took place, and a turnaround seemed possible.
In the case of the overseas proposal, Mr. Wetjen sought several significant changes last week.
And they point to several significant changes to that draft that "better protect the taxpayer," in the words of Andrew Williams, a Treasury spokesman.
Peers made several significant changes to the bill, which is ostensibly about lobbying but which also imposes new controls on how much third-party groups can spend on political campaigning during an election period.
Mr. Lazio has proposed several significant changes to the tax code, most notably making Social Security tax payments deductible for those in the two lowest tax brackets (which cover married couples who have taxable income of up to $106,000 a year).
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When the N.F.L. holds its annual meeting in Arizona next week, owners will consider several significant rules changes, but only one that can be crystallized in just one history-changing play.
Name: Market Appeal City: London Website: http://www.marketappeal.com/ In the past year Market Appeal has rolled out several significant process changes to make us more efficient.
On Wednesday, Hewlett-Packard announced several significant personnel changes, along with sharply lower revenue and narrower operating profit margins.
The 1974 season was similar to 2011, not just because of the long off-season work stoppage, but also because the league enacted several significant rule changes.
While Apple has been reluctant in the past to radically alter its smartphone, the new iPhone 5 has several significant design changes.
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