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While several previous trials have shown a relationship between anti-CS antibody responses and risk of malaria infection, this study provides the first evidence of a similar relationship between anti-CS antibodies and protection against clinical malaria.
However, results from several previous trials testing the concept have been inconclusive after surgery.
These effects are as expected and as reported in several previous trials on salmon [ 10, 13, 14].
Several previous trials of CRT have focused on patients with Class III and IV heart failure; thus, our sample is somewhat healthier than these previous trials.
Several previous trials [ 1- 3] question the safety of hydroxyethyl starch (HES) solutions compared to crystalloid solutions in critically ill patients, whereas other trials did not suggest any adverse effects [ 4- 7].
In terms of the number of visits and spacing, the qualitative stage findings of our study [ 19] and those of several previous trials conducted to evaluate ANC models that reduced the number of visits [ 15, 20, 23- 26] showed that more women in the intervention groups reported dissatisfaction with a reduced number of visits and longer spacing between them [ 20, 25].
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As several previous clinical trials carried out with valproate did not indicate any positive effect in HD, it is worth considering the design of new studies based on a well-planned treatment regime with higher dose, using valproate in monotherapy or in combination therapy with a high number of participating patients.
In several previous studies and trials, most patients had a WHO PS ≥ 2 [ 4, 5].
Induction chemotherapy involving oxaliplatin has been included in several previous neoadjuvant LARC trials [ 25– 31].
For example several previous reviews included trials in which electrical needle stimulation was performed [ 1, 2, 5] while another included data from non-randomized trials and quasi experiments [ 21].
Several previous Tai Chi trials have measured static balance improvements with the one-legged stance duration test (Hartman et al 2000; Song et al 2003), which is one small component of our balance index measure.
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