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Proteomic analysis allowed us to identify several pathways with the potential to impact these differential responses).
Thus, several pathways with the potential to regulate inflammation are known to be susceptible to programming influences.
The same miRNAs were frequently found to populate several pathways with few pathways exhibiting distinct, non-overlapping miRNA lists.
WikiPathways were excluded from the analysis due to the non-canonical or speculative nature of several pathways with significant enrichment scores.
A major consideration when manipulating any of these pathways, and in particular when attempting to target several pathways with combination therapy, is safety.
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Digital expression analysis combined with gene annotation helped in the identification of several pathways associated with abiotic stress.
HIF-1α regulates the transcription of erythropoietin (EPO), which induces several pathways associated with neuroprotection.
Interestingly, GSEA showed that several pathways associated with amino acid synthesis and metabolism were deregulated on day 2 by 5-Aza-CR (supplementary Table S2).
Table 2 shows several pathways associated with prostate tumorigenesis.
DJ-1 is a small ubiquitously expressed protein implicated in several pathways associated with PD pathogenesis.
We also identified several pathways related with cellular catabolic process and muscle development.
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