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Among the several pathways, the effect of Wnt signaling was the most controversial.
In several pathways the same reactions are active during the whole IDC (e. g. ubiquinone biosynthesis and terpenoid biosynthesis).
Since the pathways in KEGG provide a collective, rather than a species-specific, view of a pathway and further, some reactions are shared between several pathways, the occurrence of a reaction in a species is not sufficient to infer the occurrence of a pathway in a species.
Although SAA may activate several pathways, the stimulation of foam cell formation appears to be specific for FPR2/ALX since this SAA-induced response was abolished by either FPR2/ALX antagonism or siRNA against FPR2/ALX and not altered in TLR4−/− cells.
For biological reasons first: since some genes are part of several pathways, the same pathway is not necessarily active in the two species either due to the species' specificities, or because the microarray data monitor different conditions in the two species.
Similar(55)
In Arabidopsis thaliana, this transition is genetically controlled by several pathways, including the autonomous pathway, the photoperiod pathway and the vernalization pathway, which form a regulatory network [1], [2].
There may be several pathways in the retrosynthetic network linking the source metabolites to the target compounds and there is thus a need to enumerate all the possibilities.
Previous studies have shown several pathways on the basis of exisisting knowledge of the effects on the entire body of smoking [ 1].
The EGFR pathway controls several pathways, including the PI3K/Akt and MAPK pathways [ 32].
Also, KEGG analysis reveals several pathways for the susceptible line, among which the MAPK signaling pathway is significantly enriched (Additional file 5: Table S9; Fig. 4).
We observed substantially higher CoVs for several pathways for the actual map compared with the randomized map (Additional file 7: Figure S6).
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