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Dr. Jean Grassman, from Brooklyn College at the City University of New York, stated that dioxin (the active ingredient in Agent Orange) is a potent cellular disregulator that alters several pathways and disrupts many bodily systems.
Given the many functions attributed to CK1ε, it seems likely that CK1ε is an important regulator of several pathways and its function may be dependent on cell context.
Our study proves that several pathways and specific genes which might direct brain repair processes are highly upregulated in perihematomal areas.
Together with GO classifications, statistical analyses of gene sets indicate involvement of several pathways and molecules that may mediate the effects of cholinergic activity.
IL-8 gene expression is regulated by several pathways and their promoter region contains binding sequences for diverse transcription factors including IL-6, NF-κB and AP-1 [15].
The pathogenesis of human cancer is a heterogeneous process involving several pathways, and it has been proposed that the genotype may affect the clinical behavior and prognosis of the tumor [7], [8].
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RUNX1-Evi-1 promoted the primitive hematopoietic cell proliferation and apoptosis resistant, inhibited myeloid cells differentiation through synergy of several pathway and factors.
Several pathways protect and restore the integrity of the DNA.
PW1 is a pivotal mediator of the pleiotropic effects of TNF and mediates several pathways, including caspase and NF-kB activation [11], [38], [39].
By advanced search, users can combine several pathways and/or proteins and exclude other pathways and/or proteins to find the ligands and ligand clusters that binding proteins in the pathways and/or proteins that satisfy the condition.
Fig. 2 There are several pathways of emergence and entry of biofuels onto national agendas with different motivations underlying their promotion.
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