Sentence examples for several pathway components from inspiring English sources

While several pathway components are conserved among different organisms, each species also has its own specific genes, metabolites, and enzymes, and therefore has some unique set of pathways.

Several pathway components including AKT, PI3K and mTOR represent potential therapeutic targets and many small molecule inhibitors are in development or early clinical trials.

In addition, several pathway components are conserved in the related unicellular opisthokonts M. brevicollis, S. rosetta, and C. owczarzaki (Table 2).

Several conserved pathway components function to link Smo to Ci/Gli, including the kinesin-like protein Costal2 (Cos2)/Kif7 and Sufu, as well as several Ser/Thr kinases including PKA, GSK3 and CK1.

Despite these differences, however, viral challenge of the cell line also transcriptionally activated several Toll pathway components, further strengthening the evidence for the role of this pathway in antiviral defense.

Several MAPK pathway components have been reported to regulate skin tumorigenesis in this model.

Several Wnt pathway components are associated with lipid and glucose metabolism and thereby influence the development of diabetes.

The CVGs include several signal pathway components including PXY, a receptor of polypeptide signaling molecule CLE41 [ 42].

Several Shh pathway components localize within these subcellular organelles (38– 42), and the general consensus is that some aspects of vertebrate Smo-mediated Gli processing occur within cilia.

Several Hippo pathway components may thus regulate (independently or in concert) S-phase progression and quality control and thereby safeguard genomic integrity.

Investigations have shown that several Wnt pathway components are important for normal lipid and glucose metabolism and hence the pathophysiology of metabolic disorders.