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To date, SPIONs have been used to investigate several pathophysiological processes in tumor cells [8, 9], transplanted cells [1, 7, 10], or precursor cells in vivo[11 13].
The function of CYP5 is to catalyze the conversion of prostaglandin H2 to thromboxane A2, which has a role in several pathophysiological processes including hemostasis, cardiovascular disease and stroke [10].
Among these five VEGF family members, the best studied is VEGF-A that has potent angiogenic effects in several pathophysiological processes, such as wound healing and tumor metastasis.
Several pathophysiological processes, such as inflammation, haemostasis, altered metabolic and cardiac autonomic control, might play an intermediate role in the causal pathway linking depression and coronary atherosclerosis [27].
The angiogenic response is a prominent feature in several pathophysiological processes, including tumour invasion (Singer and Clark, 1999; Cavallaro and Christofori, 2000; Stupack and Charesh, 2004).
Research has identified several pathophysiological processes that contribute to the development of respiratory muscle weakness in critically ill patients [ 1, 2, 26, 27].
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Instead, data point to several possible pathophysiological processes: a covert encephalopathy, impaired physiological capability to respond to physical and mental stressors, and psychological factors related to concerns about effort exacerbating symptoms.
NADPH oxidase (Nox) family enzymes are one of the main sources of cellular reactive oxygen species (ROS), which have been implicated in several physiological and pathophysiological processes.
Recently, an increasing number of publications have demonstrated the importance of the small molecule nitric oxide (NO) in several physiological and pathophysiological processes.
The interaction of the adhesion molecule of the immunoglobulin family intercellular adhesion molecule 1 (ICAM-1) with its ligands such that the integrins LFA-1 and Mac-1 is crucial for the regulation of several physiological and pathophysiological processes like cell mediated-elimination of tumor or virus infected cells, cancer metastasis or inflammatory autoimmune processes.
NF-kB plays a central role in several physiological and pathophysiological processes.
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