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Thickening of the bowel wall may be caused by several pathologic conditions or be a normal variant [4].
NO acts as a key modulator in cardiovascular, immunological, neurological, and respiratory systems, and deficiencies in the production of NO or its inactivation has been associated with several pathologic conditions, ranging from hypertension to sexual dysfunction.
A large body of genetic analysis suggests potential association between the presence of these frequent SNPs and several pathologic conditions of diverse etiology.
It is upregulated in several pathologic conditions where, as a molecular chaperone, it is thought to provide a first line of defense against misfolded or aggregation-prone proteins [7].
Megalin's functions cover a broad spectrum and include processes that are critical during development [4], [5], [9], [10], [11] and adult life and are impaired in several pathologic conditions that compromise the kidney and the central nervous system [12], [13], [14].
Deregulation of Notch signaling leads to several pathologic conditions, including cancer [ 1].
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Changes in glycans have been detected and implicated in various pathologic conditions [23], [26].
Thus, in contrast to the proportion of CD56bright NK cells that might increase in several different pathologic conditions, over-expression of NKG2A was found exclusively in the two symptomatic TAP-deficient patients.
Haustein and colleagues included in their analysis immunocompromised children with several different pathologic conditions, including malignancies [ 3].
NFL is also elevated in several other pathologic conditions, such as frontotemporal dementia (FTD) [ 21, 22], MS [ 23], idiopathic normal-pressure hydrocephalus [ 24], ALS [ 25], and various CNS infections [ 26- 28].
Several urinary tract pathologic conditions, such as strictures, cancer, and obliterations, require reconstructive plastic surgery.
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