Sentence examples for several pathogenic pathways from inspiring English sources

Several pathogenic pathways are likely to contribute to the axonal degeneration witnessed in Alzheimer's disease, including defects in fast axonal transport resulting from enhanced production of amyloid-β (Kanaan et al., 2013).

Despite the apparent heterogeneity in these MNDs (considered below in greater detail for SMA, ALS and HSP in turn, where we describe the major causative genes), several pathogenic pathways are common among at least two of these three diseases (summarized in Fig. 1).

By the application of these techniques we have performed a complex, integrative analysis which revealed several new pathogenic pathways.

There are several common pathogenic pathways to hypertension and GDM that may be underlying the association between the two conditions.

In spite of the central role played by the CWI pathway in several pathogenic fungi, in U. maydis strains lacking elements of the CWI cascade, no apparent defects in the ability to infect maize plants have been detected (Carbo and Perez-Martin, 2010).

These and several other mechanisms could be the pathogenic pathways by which inhibition of the RAAS prevents AF. 6 8 Because of a pre-existent chronic cough, additional diagnostics were requested by his GP.

Indeed, several pathogenic microorganisms employ the DXP-independent pathway including Corynebacterium diphteriae, Mycobacterium leprae and Plasmodium falciparum, the latter being involved in the most severe form of malaria.

Current evidence indicates that several pathogenic fungi rely heavily on this pathway for virulence, but there is limited understanding of the mechanisms involved.

Similarly, newly identified environmental determinants might exert their influence through one or even several pathogenic mechanisms and might even help identify previously unappreciated pathways.

While the complete pathogenic pathways of stroke are still incompletely understood, several mechanisms (including increased glutamate, calcium overload, mitochondrial dysfunction and oxidative stress) have been proposed to contribute to neuronal damage [ 28].

They transduce downstream signals via various intracellular pathways and are likely to play an important regulatory role in several pathogenic and free-living bacteria.