Sentence examples for several mutations within from inspiring English sources

Several mutations within the ATP binding site have been described to make PKA even more similar to Akt/PKB.

Moreover, several mutations within the cyclophilin A binding loop, such as H219 and M228, have been shown to compensate to some extent for the reduced viral replicative capacity caused by T242N [28], [28].

Importantly, in chronically infected patients the HCV sequence can harbor several mutations within one single epitope.

We introduce the possibility of undergoing several mutations within one generation.

Several mutations within this region compromise this function of Ft and cause massive tissue overgrowth (Bossuyt et al., 2013).

The analysis of a collective effect of several mutations within one protein requires information on their three-dimensional (3D) environment and interaction.

Susceptibility to leprosy depends on various mutations within several genes, for example, the major histocompatibility complex (HLA-DR, HLA-DQ), tumour necrosis factor α (TNFA), Toll-like receptors (TLR1, TLR2, TLR4, TLR9), vitamin D receptor (VDR) or cytotoxic T cell antigen 4 (CTLamongamothershers [ 89, 99, 100].

In human patients, there are several mutations found within the N-terminal region of CEP290 that result in LCA, including the mutation modeled in our study (2, 3, 16, 17).

Several mutations were observed within the 2008-09 isolatessolates indicating genetic diversity (Table 1, 2).

Several mutations (including SNP variant rs561241) within a conserved HNF4A motif have been shown to perturb F7 transcription leading to hemophilia (Zheng et al., 2011 ).

Comparative genomic analysis identified several mutations in the putative promoters and within the coding region of genes which might be involved in substrates utilization (Table 2, 3).