Sentence examples for several mutant forms from inspiring English sources

We have overexpressed and purified wild type VR1 (wtVR1) as well as several mutant forms using the yeast strain Saccharomyces cerevisiae with the goal of obtaining sufficient protein for structural studies.

Schoolnik's team produced several mutant forms of the bacterium, one of which produced no pili at all and another produced superpili that bound the organisms together even more tightly than those of the normal strain.

In order to test the effects of residues surrounding the di-iron center and substrate channel on cADO's catalytic activity, we constructed several mutant forms by site-directed mutagenesis, and then determined the iron content and enzymatic activity of these mutants relative to the wild type (Fig. 4 and Table 2).

To support the conclusion that an enzymaticaly active cyclin D1/cdk4 complex is necessary to overcome growth inhibition by FGF we overexpressed several mutant forms of cdk4 defective in cyclin D1 binding together with wild type cyclin D1 (Fig. 1A, F).

Size exclusion chromatography revealed that several mutant forms are less stable than WT MscS as discussed above.

In the present work, extensive experimental data are available for several mutant forms, and therefore, in principle, the wild-type enzyme should be an adequate reference state.

We created a trypanosome clathrin heavy chain hemizygote and several lines expressing mutant forms of Rab5 and Rab11, described previously.

The Akt pathway represents one of the most frequently dysregulated pathways found in human cancer (Altomare and Testa, 2005; Cheng et al, 2005) and is a critical mediator of the survival and proliferative effects of several oncogenes including mutant forms of the EGF receptor, Ras and PI3-kinase, as well as the Bcr-Abl fusion protein (Yuan and Cantley, 2008).

In an attempt to explain the molecular basis for agonicity and antagonicity in the androgen receptor, and the changes on biological activity of subtle modifications at the ligand and receptor (mutations) level, molecular dynamics simulations were performed on the androgen receptor wild type (WT), and T877A and W741 mutant forms, complexed with several non-steroidal androgens.

In PMD, for example, several studies have shown that the mutant forms of the structural myelin protein proteolipid protein (PLP) and its alternatively spliced isoform DM20 accumulate in the ER of oligodendrocytes.

Levin et al. identified several mutant S. rosetta strains that cannot form rosettes.