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Several mouse and rat models have been used to gain a better understanding of the mechanisms underlying disease development, which is essential for rational drug design and vaccination strategies.
Several mouse and human erythroid cell lines have been established.
For example, Valcourt and colleagues undertook an extensive analysis of TGFβ1-induced EMT in several mouse and human epithelial cell lines [8].
Several mouse and cell culture experiments have demonstrated that perifosine has antitumor activity, which is especially pronounced when combined with radiation [6] or temozolomide [7].
More recently, studies show several mouse and human tumor cells express certain TLR members and the TLR activation by bacteria or bacterial component seemed to promote tumor progression[8], [15], [16].
DisGeNET also includes data on several mouse and rat disease models where alterations in this gene have been described.
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For example, in several mice and voles [36], 'exploratory excursions' are observed, i.e. short movements outside the home range of an animal with the aim to explore neighbouring habitats.
Using ten gall bladders provided by a nearby crocodile farm, he tested moderate concentrations of the substance on several mice and a baboon over a week and found no signs of toxicity, much less death.
Data represent two independent experiments using several mice and glands in each.
Several studies have also demonstrated that DES exposure during the fetal and prenatal stages induces tumor formation on estrogen-sensitive tissue in several mice and hamsters models.
We also observed several mice and rats in this study where the diameter measurements plateaued, but the volume/length ratio continued to increase.
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