However, unlike Drp1 mutants, Marf mutant NMJs exhibit severe morphological defects (see below).
MC neurons are still born in the ceh-19 mutants but display various morphological defects.
Second, although the secreted sulfatase-deficient skeletons appeared overall to be patterned normally (Fig. 4A and B), we did observe several highly specific morphological defects at the midline, including sternal fusion and defective basisphenoid patterning.
The identification of filamin-A and vimentin as substrates is consistent with the observation that ectopic expression of p94 in several different culture cells causes morphological defects accompanied by proteolysis of several cytoskeletal proteins, including filamin-A and fodrin [ 40].
Our finding that half of the mutant embryos studied had multiple morphological defects could have several explanations.
Severe malformations include gross morphological defects (Fig. 5F).
The results showed good crystalline behaviors and morphologies without any identifiable morphological defects.
A benefit of hybrid multilayers (ML) is that the separation into several oxide layers leads to a decoupling of morphological defects, e. g. caused by particles, which prolongs the permeation path trough the barrier [8].
In fact, by using light microscopy analysis they observed both in human and animal model the same morphological defects, including complete or partial absence of the mitochondrial sheath, coiled tails, several flagella, and bicephalic sperm [ 19].
