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*Kininase, an enzyme that blocks several molecules that create the itch sensation and swelling when skin is injured.
During the past decade, several molecules that contribute to lung cancer progression and metastasis have been identified.
Several molecules that were initially identified and studied in the immune system have been shown to have essential functions also in the bone.
Here we review structure-based approaches underlying the development of several molecules that are currently in clinical trials, including the cMet inhibitor ARQ197 and the Bcr Abl inhibitor ponatinib.
In order to search for alternatives to the sulfoxide moiety in the long side chain of pure antiestrogens, several molecules that may interact with water in a fashion similar to ICI164,384 were designed and it was found that compounds with the carboxy, the sulfamide, or the sulfonamide instead of the sulfoxide moiety also functioned as pure antiestrogens.
Several molecules that can cause similar stage-specific morphological phenotypes in trypanosomes have been identified.
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Thus, the natural extract of such a living fossil, shaped by natural selection during several millions of years, may contain several unique molecules that are less disruptive than synthetic products and better suited for fitting with biological systems [40].
Several studies showed that dietary n-3 PUFAs and EPA inhibit the ability of macrophages to secrete several effector molecules that may be involved in the pathogenesis of atherosclerosis (18, 19).
The chlorophyll molecules are grouped into antenna complexes, clusters of several hundred molecules that are anchored onto the thylakoid membrane by special proteins.
The innate immune response comprises a complex of several player molecules that assist the host to neutralize infectious assaults by different microbes.
We recently disclosed the synthesis and biological activity of several small molecules that did not contain any peptide bond and mimic the tripeptide RGD.
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