Sentence examples for several molecular changes from inspiring English sources

Melanoma progression is associated with several molecular changes including CCN1/CYR61, MCAM/MUC18 and PAR-1 [8], [44] [46], [46].

Importantly, several molecular changes during aging of mammalian cells are identified in aging Aplysia neurons suggesting that molecular changes associated with aging involve several conserved mechanisms.

Although characteristic patterns of DNA changes are caused by exogenous mutagens in both lung cancer types for several molecular genetic changes, such as G-protein pathways and MYC genes, differences between SCC and SCLC have been shown (Greenblatt and Harris, 1995).

In addition, several novel molecular changes associated with clinically relevant endpoints have been demonstrated.

However, several molecular and cellular changes, including oxidative stress, mitochondrial dysfunction and apoptotic processes might be involved in neuronal degeneration [1], [6], [7].

In humans, long-term DR causes several metabolic and molecular changes that protect against age-related pathologies, including changes in markers for type 2 diabetes, hypertension, cardiovascular disease, cancer, and dementia (Cava & Fontana, 2013).

Risk variants of TCF7L2 SNPs might be associated with several types of molecular changes relevant for T2D and our study addressed only one of these types, mRNA expression of alternative splicing forms.

Motor neuron degeneration occurred in parallel with signs of astrocyte and microglia activation, and was associated with several morphological and molecular changes, including neurofilament and peripherin abnormalities in the cell body and the axon, misplaced and flattened nuclei, morphological changes of the Golgi apparatus, and expression of the transcription factors p53 and ATF3.

Living organisms adapt to the environmental stress conditions by undergoing several phenotypic, physiologic and molecular changes, which requires precise regulation at the transcriptional, post-transcriptional and translational levels.

Although diminished satellite cell numbers have been implicated in the age-related decline of muscle tissue regeneration, several reports identified key molecular changes within Notch and P-Smad3 signaling in the aged endogenous populations (Conboy et al., 2003; Carlson & Conboy, 2007b; Carlson et al., 2008).

Microarrays and cDNA-AFLP analyses are highly sensitive tools used in several molecular studies to detect changes of gene expressions in polyploids; however, there is experimental variability arising from PCR in the analysis of a large number of bands in AFLP, and from the variability of fluorescent signals in microarrays.