The number of affected substrates, the severity of knockdown phenotypes across several model systems and implications in disease and development all point to a critical role of Naa10 in normal cell function.
Using psoralen-conjugated triplex-forming oligonucleotides, we initially demonstrated the feasibility of triplex-targeted mutagenesis in several model systems.
The validity of this approach was confirmed by computer simulation on several model systems.
Seung K. Kim M.D., Ph.D. Current Research and Scholarly InterestsWe study the genetics of pancreatic islet cell differentiation using molecular, embryologic and genetic methods in several model systems, including mice, embryonic stem cells, and Drosophila.
Current Research and Scholarly Interests We study the genetics of pancreatic islet cell differentiation using molecular, embryologic and genetic methods in several model systems, including mice, embryonic stem cells, and Drosophila.
The performance of the new algorithm is illustrated with several model systems and also by relaxing a defect in bulk silicon.
Recent studies in several model systems have begun to decipher the 'cis-regulatory codes' of CRMs involved in various developmental processes.
In this work, we present a review of our most recent research on some of the factors that can influence a chemical reaction in confinement through the study of several model systems.
Metastasis is a complex clinical and biological problem presently under intense study, and several model systems are in use to experimentally recapitulate and dissect the various steps of the metastatic process.
Thermal degradation of astaxanthin has been studied in several model systems (Niamnuy et al. 2008).
Here, we review several model systems that have been developed to advance the understanding of the role of SNCA expression levels in the etiology of synucleinopathies.
