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The rice community has developed several libraries of CSSLs and these have proven to be a powerful resource (Tian et al. 2006; Ahn et al. 2002; Ghesquiere et al. 1997; Sobrizal et al. 1996; Ali et al. 2010b).
Several libraries of TEM-1 β-lactamase variants were generated by error-prone PCR, and variants with increased protease resistance were obtained by raising temperature or guanidinium chloride concentration during proteolytic selections.
In an attempt to identify other drugs that inhibit the function of AQP4 in water transport, Mola et al [15] developed a functional high-throughput assay based on the measurement of osmotically-induced cell volume changes to screen several libraries of drugs and identified four blockers of AQP4-mediated water transport.
A combination of several libraries of read-pairs with different insert sizes is often used to produce high-quality assemblies (Butler et al. 2008; Bresler et al., 2012).
An even more complete picture including SVs of a larger size and more complex rearrangements will require paired-end sequencing of several libraries of different insert sizes [ 28].
To extend the repertoire of mouse mammary gland expressed miRNAs, we have constructed several libraries of small miRNAs allowing the cloning of 455 sequences.
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Wellington and colleagues are continuing screening of several libraries for additional modulators of ApoE and ABCA1.
By reassembling leaves of a sacred manuscript divided among several libraries, Jacob Dalton of the University of California at Berkeley has been able to reconstruct one of the earliest tantric manuscripts, which contains a startling, and seemingly very un-Buddhist, manual for performing human sacrifice.
Overall, most compounds obey Lipinski's and Veber's rules yet for several libraries the percentage of compounds violating these rules is not negligible (Platinum Collection 6.4, 7.4 %, respectively, and Prestwick Chemical Library® 7.9, 13.5 %, respectively).
Professor Golb has suggested that the scrolls were actually the product of several libraries in Jerusalem and were taken to the caves around the time the city fell to the Romans in the year 70.
The Ahmed Baba Institute, one of several libraries and collections in the city containing fragile ancient documents dating back to the 13th century, is named after a Timbuktu-born contemporary of William Shakespeare and houses more than 20,000 scholarly manuscripts.
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