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In order to leverage the power of multiple transcriptomes reported by several laboratories using different patients and protocols, more sophisticated methods like the extension of GSEA presented here, should be used in order to overcome the shortcomings of overlapping individual DEG approach.
The transcriptional responses of rice and barley genotypes were also characterized independently by several laboratories using various microarray platforms [ 13- 15].
Although the transcriptional repertoire of Plasmodium sporozoites has been investigated in several laboratories using different techniques, including cDNA libraries, SSH, microarrays and proteomics, only the microarray data has provided information concerning the level of gene expression [ 9].
After the identification of a first candidate [ 12], recent efforts from several laboratories, using both bioinformatics screens and translocation assays have resulted in a list of possible effectors [ 13- 16].
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In the past decade, several laboratories used gene expression profiling to define the molecular nature and identify prognostic signatures for HCC.
7 In the past decade, several laboratories used gene expression profiling to define the molecular nature and identify prognostic signatures for HCC.
Several laboratories use magnetic resonance imaging to more accurately study the apparent diffusion coefficient, the distribution of AT in the body, the volume of AT in the different regions, and the different rates of diffusion (Steidle et al. 2011).
They reported the results for 22 iPSC lines, made by several different laboratories using multiple reprogramming methods.
Up-regulation of pro-collagen type I by both ROS and HNE in activated HSC/MFs is a relevant finding that has been confirmed by several different laboratories using either cells of human or rat origin.
Our initial supposition that the large proportion of undiagnosed cases might be caused by the presence of undiscovered pathogens does not appear to be the case; independent testing of numerous samples at several research laboratories using multiple different techniques, including next-generation sequencing, did not identify any novel infectious agents.
Functional validation of non-synonymous variants could be performed using several laboratory models, using either whole organisms (such as yeast, Drosophila, fish or mice), or cells (such as cell-based models derived from humans or other organisms and in-vitro-differentiated cells).
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CEO of Professional Science Editing for Scientists @ prosciediting.com