Sentence examples for several key pathways from inspiring English sources

DNA damage/repair constitutes several key pathways working in concert to eliminate DNA lesions and maintain genome stability and integrity.

The balance between cell survival and death is essential for cancer formation and is determined by several key pathways that impact on different stages of gene expression.

These posttranscriptionally regulated mRNAs are functionally coordinated, mapping to several key pathways characteristic of the myeloblast phenotype.

This has implication for disease pathogenesis, since the PARK proteins influence several key pathways of cellular function including oxidative phosphorylation, apoptosis, synaptic transmission, and transmission of nerve impulse, all pathways that seem to be more affected in male PD.

Runx proteins contribute critically to the transduction of developmental signals via several key pathways, including those mediated by TGFβ/BMP, FGF, Notch, and Wnt proteins [22] [32], each of which is essential for embryogenesis and stem cell regulation.

Other biological activities also take place in chloroplast including the production of starch, certain amino acids and lipids, vitamins, certain pigments in flowers and several key pathways of sulfur and nitrogen metabolism [3].

Acid-tolerant Saccharomyces cerevisiae was engineered to produce lactic acid by expressing heterologous lactate dehydrogenase (LDH) genes, while attenuating several key pathway genes, including glycerol-3-phosphate dehydrogenase1 (GPD1) and cytochrome-c oxidoreductase2 (CYB2).

Increasing evidence suggests that phosphorylation participates in almost every step in the signal relay from Smo to Ci/Gli, and that differential phosphorylation of several key pathway components may be crucial for translating the Hh morphogen gradient into graded pathway activities.

Pathways with greater diversity in RD cancers relative to pCR cancers included basal-cell-carcinoma, which includes genes from the Hedgehog, Wnt, TGF and p53 signaling pathways, folate biosynthesis, and dorso-ventral axis formation pathway involving genes from several key signaling pathways including the MAPK and NOTCH.

All the three substrates supported growth and PHB production by C. necator, but substrate-specific effects were observed for cell mass production, PHB accumulation, and protein expression levels of several key metabolic pathways, including glycerol metabolism, the fatty acid β-oxidation pathway, the Glyoxylate Shunt, and hydrogen (H2) synthesis pathways.

Mutations in these genes have been functionally linked to several key molecular pathways implicated in other neurodegenerative disorders, including mitochondrial dysfunction, protein accumulation and the autophagic-lysosomal pathway.