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Wnt4 is a member of the WNT family of intracellular growth and differentiation factors, which regulate several key developmental steps.
In utero arsenic exposure associates with the expression of several key developmental genes in the fetal placenta.
Consistently, nfs expression is altered in mutants of several key developmental regulators necessary for appropriate expression of sporulation genes.
In summary, we present a rigorous analysis of the genomics of the Drosophila group B transcription factor Dichaete, highlighting regulatory input into several key developmental pathways.
There are several key developmental differences in the host response to infection that clearly delineate neonatal sepsis as a separate entity from adult sepsis.
In this study, we identified several key developmental and stem cell regulatory genes as potential biomarkers of arsenic exposure in the fetal placenta.
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Among the factors implicated in the maintenance of pluripotency are the Polycomb group (PcG) proteins that repress expression of several thousand key developmental genes in ESCs (Ku et al., 2008).
Focused genetic studies of model streptomycetes have revealed several tens of key developmental genes (Flärdh & Buttner, 2009; Chater, 2011; McCormick & Flärdh, 2012).
In this study we used the PC12 model to address several key aspects of the developmental neurotoxicity of CPF.
Vertebrate genomes contain several Notch paralogs, which control key developmental decisions at numerous stages and in diverse tissues and organs (Andersson et al., 2011; Gazave et al., 2009).
Several key processes underlie these distinct developmental events and the resulting features of form that emerge (e.g., the through-gut formed subsequent to gastrulation or the heart formed during organogenesis).
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