Sentence examples for several isoforms are from inspiring English sources

Trio and Kalirin (also known as Duo), both having several isoforms, are multidomain containing Rac GEFs that share high sequence homology.

The mechanisms controlling calcium-induced inotropy are probably several fold, and include activation of protein kinase C [ 8], of which several isoforms are calcium dependent.

Multiple peptide identifications could belong to two or more isoforms and it is quite possible that several isoforms are present in the same sample, especially when multiple tissues are studied.

Unfortunately, while specific si-RNA inhibited significantly the expression of these isoforms, diminution of any of these isoforms alone was capable to prevent acadesine effect's on cell viability (not shown), suggesting that the combination of several isoforms is necessary to transduce the effect of acadesine.

Thus, PKC activation involving several isoforms is likely to be responsible for some of the pathologies in diabetic retinopathy.

Several isoforms were rare and only encoded by a single transcript, but some were highly expressed, which reflects their relative frequency in the gluten transcriptome.

While several isoforms were encoded from the same gene, sometimes the different protein products could not be distinguished by the identified peptides.

Rho family proteins are engaged in cytoskeletal reorganisation and enhanced expression of several isoforms was observed in metastatic tumour cells (Fritz et al, 1999).

However, because of the presence of multiple splice events common to several isoforms is completely impossible to design a qRT-PCR assay to discriminate one against each other.

Given that several isoforms were only found in one species, greater sequencing depth is required for our analysis to overcome incomplete assemblies and sampling biases, previously observed in genomic sequences of Pseudomonas syringae strains [ 47].

Interestingly, several isoforms were detectable in human tumour data both before and after treatment, and in both time points of our experimental system, and transcripts show great variation in composition of functional domains (Table  1).> -wrap-foot> *Nonsense mediated decay; ^Processed transcript; ND not detected, NTD N-terminal domain, ZF zinc finger, LBD ligand binding domain.