This assumes 10 independent comparisons and should suffice for a nominal 0.05 type I error protection for five independent SNPs that were analysed in several correlated inheritance models and haplotypes.
The approach is illustrated with several inheritance trees: for sorting, graph algorithms, string matching, and network flow.
Different inheritance models (codominant, dominant, recessive, and additive) were tested.
We tested different genetic inheritance models and a dominant model was applied in the final analyses.
Genetic analysis filter was used to construct different inheritance models.
Several association studies support the polygenic inheritance model of breast cancer, showing increasing risk of disease when many predisposition variants of low effect size were combined [ 11, 40].
These results illustrate that the binomial inheritance model can also describe the statistics associated with heteroplasmic nucleoids of arbitrary size, over a timescale of several dozen cell divisions (suitable to describe the developmental process).
Table 5 shows the relationship between CXCL9-11 polymorphisms and liver stiffness under a recessive inheritance model.
In this paper, we extend our previous work with inheritance modeling.
Inheritance modeling suggested a co-dominant mode of inheritance in all cohorts.
