Sentence examples for several important pathways from inspiring English sources

Analyzing the data within the KEGG PATHWAYS and GO revealed several important pathways and functions reflecting the aggressive and resistant phenotype of mesothelioma and some of the novel and most interesting findings will be highlighted below.

This chapter will focus on several important pathways of ischemia/hypoxia signaling, specifically with regard to features analogous to this pathway and chemically induced toxicity.

According to above-mentioned properties, QCT could serve as the starting material of inositol or its derivatives to participate in several important pathways and may act as a potential anticancer or antidiabetic drug lead to arrest or reverse these diseases.

As we expected, several important pathways related to nutrient metabolism were found to be significantly affected (Table 5).

Src is upstream of several important pathways that have been implicated in the neoplastic phenotype [39], and it is likely that targeting Src for knock-down also has effects on these downstream signaling pathways, including the Ras/MAPK, AKT/PKB, and STAT3/Myc pathways.

Several important pathways have been revealed playing critical roles in the diabetes progression.

We used iTRAQ MS/MS in conjunction with custom peptide db searches to quantitatively characterize several important pathway components for berry ripening previously described at the transcriptional level and confirmed expression patterns for these at the protein level.

Survivin also acts as a downstream target protein involved in several important signaling pathways, the PI3K/Akt pathway, mTOR pathway, ERK pathway, tumour suppressors (p53, PTEN) and oncogenic (Ras, Bcl-2) signaling pathways.

Identifying several genetic loci revealed that several important biological pathways are involved in AMD pathogenesis, such as the cholesterol, lipid metabolism pathway, complement pathway, extracellular matrix pathway, oxidative stress pathway, and angiogenesis signaling pathway in [ 20– 22], which provides a foundation for systematically analyzing the biological processes underlying AMD.

TNF-α regulates several important signalling pathways in cardiomyocytes, such as the NFκB pathway, through binding to the TNFRs.

These and other important viral miRNA targets are briefly listed in Table 2. Using KEGG Mapper, we found that the target genes in VIRmiRtar were enriched in several important cellular pathways including Metabolic (hsa01100), cancer (hsa05200), viral carcinogenesis (hsa05203) pathways with 188, 96 and 84 hits, respectively.