Here we consider simple disease spreading processes on empirical time-varying networks of contacts between individuals, and compare the effect of several immunization strategies on these processes.
Finally, the Sjc23 was the first tetraspanin identified in S. japonicum 20 years ago [22], [23] and it, as well as its homologous Sm23 from S. mansoni, has been regarded as a vaccine candidate which has been tested in several immunization and challenge trials in animals [24] [28].
To contain the outbreak, several immunization campaigns have been conducted across the country.
However, to promote long lasting protection, several immunization boosts may be required and in addition to this, production and purification of these components is time-consuming and expensive.
Several immunization strategies against atherosclerosis have been developed, and different techniques and targets have been chosen to determine their protective effect in mice and rabbits [ 53, 54].
Young animals (of Indian origin) from our colony that were positive for the Mamu-A26 serotype appeared completely resistant to the disease even after several booster immunizations.
Here we compared several genetic immunization protocols for their potential ability to generate high levels of antibodies against proteins expressed in their native form.
A direct debilitating effect of the autoantibodies is unlikely, since only several re-immunizations induce the onset of the disease and the presence of antibodies does not directly correlate with salivary gland dysfunction [5].
