Sentence examples for several immune cell from inspiring English sources

A new study shows that the PTPN22 coding variant associated with autoimmunity is a loss-of-function allele that causes the protein tyrosine phosphatase encoded by PTPN22 to undergo accelerated degradation, resulting in enhanced signaling in several immune cell types.

RASGRP1 is involved in the development and activation of several immune cell types [36], [37].

MRI-active and MRI-inactive patients showed significant differences in the relative composition of several immune cell subsets, including TCRαβ+CD4+CCR7−CD45RA− peripheral memory T-cells [3] and a reduction of CD8low+CD56+ natural killer cells [4].

In fact, several immune cell types, including neutrophils [ 37] and DCs [ 38, 39], are known to generate exogenous antigenic peptides.

The lymph nodes house several immune cell types including B cells, T cells, plasma cells, macrophages, reticular cells and white blood cells.

The disease-ameliorating effects were accompanied by reductions in several immune cell subsets (including B1 cells) and reduced dendritic cell maturation.

Because TNF-α is produced by several immune cells during inflammation, our work elucidates aspects of the physiologic mechanisms of Treg function.

Syk is an important downstream signal molecular of moesin (Urzainqui et al., 2002; Matsumoto and Hirata, 2016) and can regulate calcium signaling in several immune cells (Kulathu et al., 2008; Krishnan et al., 2009).

Although LAIR-1 has been described in several immune cells, including subsets of myeloid dendritic cells, its expression has never been investigated in pDCs.

In vitro studies have subsequently shown that MSCs actively inhibit the function of several immune cells through secreted cytokines, growth factors and enzymatic action, although controversy exists on the identity of the responsible mediators [7], [8], [9], [10], [11].

The increase of several immune cell-derived factors, such as interleukin-1 (IL-1), IL-6, IL-8, IL-10, and tumor necrosis factor alpha (TNF- α), has been described in tumor microenvironment: they sustain inflammatory process, contribute to tumor progression, and also exert proangiogenic activity [ 95, 96].