Epstein-Barr virus (EBV) causes infectious mononucleosis and is linked to several human malignancies.
NPM1/B23 deregulation is implicated in the pathogenesis of several human malignancies.
Many studies have shown that MYBL2 is high expresssion in several human malignancies including pancreatic ductal adenocarcinoma (PDAC).
The insulin-like growth factor-1 receptor (IGF-1R) plays a key role in proliferation, growth, differentiation, and development of several human malignancies including breast and pancreatic adenocarcinoma.
These and other analyses have identified hundreds of novel somatic mutations across several human malignancies [21].
Epstein-Barr virus (EBV) infection is associated with several human malignancies.
Several human malignancies are associated with Epstein-Barr virus (EBV) and more than 95% of the adult human population carries this virus lifelong.
Aberrant hypermethylation of microRNA genes has been reported for several human malignancies, including colon cancer [15], breast cancer [16], acute lymphoblastic leukemia [17], and chronic myelogenous leukemia [18].
Methylation-associated inactivation of RASSF1A has been frequently observed in several human malignancies including sporadic CRC [33], [34], [35], [36], [37].
Nonetheless, as TRKB is overexpressed in several human malignancies, including neuroblastoma, pancreatic and prostate adenocarcinoma, it has been suggested as a potential target for anticancer therapy [43], [44].
Epstein-Barr Virus (EBV) latent infection is associated with several human malignancies and is a causal agent of lymphoproliferative diseases during immunosuppression.
