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Cerebellar involvement in micturition control has been reported by several human brain imaging studies [17 19], but its exact role remains elusive.
The test tube finding, reported in the current Cell, could help explain the formation of prions--the tangled proteins that are implicated in mad cow disease and several human brain disorders--and eventually may lead to a way to smooth out these rogue proteins.
Although TPH1 has a higher catalytic rate than TPH2 [20] and since in several human brain areas, TPH1 mRNA is more abundant than TPH2 [21], TPH1 protein was not detectable by immunohistochemistry [22].
NR4A2, also known as Nurr1, encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily that is expressed in a complex pattern in the cortex, which may be different in mouse and primates [43], [44], and could be involved in several human brain diseases [45], [46].
The two novel transcripts, FMR5 and FMR6, were validated in several human brain regions.
FMR5 was expressed in several human brain regions from unaffected individuals and from full and premutation patients.
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Later, LRP1b expression was reported in several human tissues (brain, adrenal gland, salivary gland, testis, skeletal muscle, lung, kidney, small intestine, prostate, thymus, heart, stomach) [5].
Our results are also consistent with the modular organization reported in several recent human brain networks studies.
Next, we assessed MCT8 expression in the brain using several comprehensive human brain transcriptome data sets.
But several yards away, a glass case proudly displayed several dozen human brains.
"These people have relatives," she replied when I asked why they are hidden from view, "and it seems wrong to show the public their brains". But several yards away, a glass case proudly displayed several dozen human brains.
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