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Our observations are consistent with a broad epigenetic abnormality of poor quality human sperm in which levels of DNA methylation are elevated at numerous sequences in several genomic contexts.
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Our study aimed to characterize the genomic methylation patterns in various genomic contexts of PC.
Examining the insect TipE gene family reveals several key evolutionary events that characterize the evolution of genes within their genomic contexts: intronic nesting, escape from nesting, overlapping exons, retrotransposition, translocation, gene loss, coordinated regulation, and conserved synteny.
b Comparison of the genomic contexts of the bacterial cysteine degradation systems among genomes of Enterobacteriaceae bacteria.
Retroposons in new genomic contexts are likely to interfere with the host genome function [1].
Combining the genomic data with characterization of the fruit identified several genomic regions that are linked to desirable traits.
Turner, D.J. et al. Germline rates of de novo meiotic deletions and duplications causing several genomic disorders.
This shows that the modes of action of FIGL1 and FANCM are differently affected by genomic contexts.
We also investigated the distribution of CA fragments across genomic contexts bound by different TFs and found an overall consistent pattern between CA and GE level.
Therefore, we examined the overall distribution of single-cell CA fragments across different genomic contexts, as well as the expression levels of the putative regulated genes.
Thus, the combined signatures from scCAT-seq well reflect known processes and are useful to assess the transcriptional state of genes within different genomic contexts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com