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Several genetic polymorphisms have been described to explain differences in susceptibility and severity of encapsulated pathogen-related diseases.
Several genetic polymorphisms in vasculitis have now been described.
PON1 presents several genetic polymorphisms that influence its ability to hydrolyze OPs as well as its level of expression.
Several genetic polymorphisms including point mutations and deletions have been reported and studied in association with lung cancer with conflicting results in populations from different ethnicities [43] [45].
Several genetic polymorphisms in gene coding for enzymes involved in the Hcy metabolism are demonstrated or suspected to be associated with HHcy [C677T and A1298C in 5,10-methylenetetrahydrofolate reductase (MTHFR), A2756G in methionine synthase (MTR)].
Several genetic polymorphisms significantly affecting AMD has been identified.
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Genome-wide association studies (GWAS) and candidate gene analyses have led to the discovery of several dozen genetic polymorphisms associated with breast cancer susceptibility, many of which are considered well-established risk factors for the disease.
Genome wide association studies (GWAS), have discovered several new genetic polymorphisms affecting breast cancer risk [ 1- 3].
Genomewide association studies already identified several distinct genetic polymorphisms associated with Crohn's disease.
It has been found that several MDR1 genetic polymorphisms are related to a functional variation of the protein [ 15– 17, 21].
The coding sequence of the VDR protein is comprised of eight exons, and several (>60) genetic polymorphisms have been identified [ 5, 37].
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