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A transcription factor may act on several genes with equal or different thresholds.
Several genes with putative or validated roles in root hair development showed increased expression under Mn-deficient conditions but decreased expression in Fe-deficient plants (DER1, AGP14, FLA9).
Also in this genomic region, several genes with functions compatible with disease resistance were identified (Additional file 7: Table S2).
CONCLUSION:We identified a HOX-centric network associated with serous EOC risk containing several genes with known or emerging roles in serous EOC development.
Overall, the in silico search for candidate genes, in the two QTL regions (qBK1_628091 and qBK4_31750955) identified in this work, highlighted several genes with functions associated to disease resistance that could represent candidates for bakanae resistance.
The fact that Asgard archaea share several genes with more complex life forms suggests that their cells may feature something similar to the structures that make eukaryotes complex, only more simplified.
In addition we identified several genes with potential to guide prognosis and therapy.
Several genes with lesser mutation rates were also identified (Table S4).
Several genes with known anti-proliferative and/or pro-apoptotic activities were induced: REDD1/DDIT4, p21CIP, stratifin, cyclin G2, GDF15.
A comparison of the Saccharomyces cerevisiae ERG3 to the Chlamydomonas genome revealed several genes with significant protein sequence homology.
In Drosophila several genes with visible phenotypes, for which inactivation does not affect viability, serve as excellent PEV reporters.
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