Sentence examples for several epigenetic changes from inspiring English sources
Several epigenetic changes in host epithelial cells may be caused by increased butyrate production from probiotic strains [ 53].
On the other hand there are several reports of epigenetic changes impacting on microRNA expression.
Efforts of this type have already identified several genetic and epigenetic changes that seem to occur at the transition from normal mucosa to precancerous lesions.
Most clinically manifest cancers have accumulated several genetic and epigenetic changes, which confer them a growth advantage over their neighboring cells (Hanahan and Weinberg, 2011).
There are several factors involved in epigenetic changes, but one of the most important is the histone deacetylase (HDAC) activity regulation because it changes the genetic expression.
Several genes that show epigenetic changes in response to MDV infection have been associated with p53.
In different cell systems, and using different mechanistic approaches, we previously demonstrated that an impaired RARα signalling, due to derangement/loss of RARα itself, confers an exacerbated repressed chromatin state, marked by repressive epigenetic changes at several RA-responsive genes downstream of RARα [7] [9].
Similarly, several environmental factors produce epimutations (epigenetic changes associated with disease); factors relevant to IBD include smoking, the microbiota, and diet.
This study was designed to compare epigenetic changes among several closely related species of Darwin's finches, a well-known example of adaptive radiation.
They would accumulate several genetic alterations and probably epigenetic changes involving inactivation of regulatory elements of key genes participating in cell-cycle regulation and cell growth control (Seike et al, 2000).
In many tissues, HIF-1 α may not be sufficient to induce CAIX and only several oncogenic steps associated to epigenetic changes leading to chromatin remodeling will 'uncover' the ca9 gene and make it permissive and inducible by HIF-1.
