Sentence examples for several distinct sequences from inspiring English sources

We next used shRNA-expressing lentiviruses with several distinct sequences targeting FAK to stably knock down total FAK levels and phospho-FAK397 (Fig. 1C).

The presence of the multiple ON1 genotype lineages in Kilifi, some occurring as multiple phylogenetic clusters or several distinct sequences, suggests that there have been multiple introductions of the genotype into the region.

Structure function investigations of IFN α have found that the differences in activity were correlated with their ability to bind the receptor, and several distinct sequence regions may involve the interactions between ligand and receptor or ligand and ligand (Karpusas et al. 1997; Meister et al. 1986; Radhakrishnan et al. 1996).

Genetic heterogeneity is the phenomenon that several distinct sequence variants may give rise to the same phenotype (Burrell et al., 2013); one refers to allelic heterogeneity if these variants are located in the same gene, and to locus heterogeneity if they occur in several distinct genes.

However, a CRE-driven reporter assay is a highly simplified system with respect to transcription of cellular genes, where several distinct promoter sequences control this process.

In other cases, several distinct viral sequences were detected in different individual bats of 1 species, such as Miniopterus minor bats sampled from a single colony in Kenya (n = 53), which harbored 6 distinct viral sequences.

A specifically tailored reference genome was used for reliable variant identification, revealing several distinct genomic sequence changes which associate with fast bacterial adaptation.

For example, the PyroNoise method (Quince et al., 2009) uses a maximum likelihood approach to decide whether a set of flowgrams is likely to result from one or several distinct underlying biological sequences.

These sequences shared the AGAGA motif or were generally A-rich, and the authors proposed that dispersed along the X chromosome are clusters of several distinct but degenerated sequence motifs, for which the MSL complex exhibits a complete range of affinities.

Since Cenococcum is a complex genus that encompasses much genetic diversity and is suspected to include several distinct lineages [61], LSU sequences for each species of Cenococcum in our sample were generated using the LR0R, LR6 and LR3 primers [62] and included in a Dothidiomycete phylogeny (G. Mugambi and S. Hundhorf, unpublished).

Several distinct poly Q encoding sequence patterns were observed in LCC-6, T47D, and MDA-MB157.