Sentence examples for several disease models from inspiring English sources

The role of AQs in virulence and the severity of infection has been demonstrated using several disease models.

Furthermore, studies have shown that hydrogel-encapsulated cells were functionally effective in several disease models [11],[11],[11].

Inhibitors of the enzyme soluble epoxide hydrolase (sEH) reduce fibrosis in the heart, pancreas and kidney in several disease models.

Draft and complete genome sequences from bacteria are key tools to understand genetic determinants involved in pathogenesis in several disease models.

Immature myeloid cells (IMCs) and dendritic cells have been shown to be actively involved in angiogenesis in several disease models in mice and humans.

The delivery of ER chaperones or active UPR components using adeno-associated virus (AAV) has demonstrated outstanding beneficial effects in several disease models (e.g., neurodegenerative conditions, eye disorders, and metabolic diseases).

Deletion of Ddit3, the gene encoding CHOP, has also been reported to reduce cell death in multiple tissues in several disease mouse models associated with ER stress including a neurotoxin-induced Parkinson disease model, the demyelinating Charcot Marie Tooth 1B mouse model, and a model of diabetes (36– 36).

Fairfield et al. succeeded in identifying causative mutations in several ENU-induced mutants by exome sequencing, but failed to do so in several spontaneous disease models [ 70].

Indeed, chronic stimulation of the innate immune system via TLR4 leads to the induction of immunosuppression [ 29], and several plant polysaccharide with immunomodulatory activities were recently found to have therapeutic effects in several autoimmune disease models, including EAE [ 30- 34].

This review describes the recent use of microdialysis in several neuropsychiatric disease models including schizophrenia, stress, addiction and depression and demonstrates the ability of this tool to target neurotransmitter systems and brain regions implicated in psychiatric illness.

A broad range of infectious and autoimmune diseases that involve IL-1β have been associated with inappropriate activation of the inflammasome [12, 14, 15], while in several other disease models in which IL-1β plays a crucial role, the inflammasome appears not to be involved [16, 17].