Sentence examples for several different subtypes of from inspiring English sources
First, ALK is strongly expressed in several different subtypes of human breast cancers, in a pattern not consistent with normal tissue [ 84].
It is now clear that several different subtypes of CRC exist, defined by the acquisition of specific different genetic abnormalities that drive the cell transformation.
There are several different subtypes of MDS (e.g. refractory anemia; refractory anemia with ringed sideroblasts) and the number has been changing as diagnostic tools have improved (Swerdlow et al., 2008).
In this mouse model, we observe that when either alleles of p53 or Pten were deleted individually it did not result in any tumor formation but in combination several different subtypes of LPS were formed.
Recently, two groups reported that frequent somatic mutations in the CREBBP and EP300 genes encoding histone acetyltransferases (HATs) were present in primary tumours and acquired at relapse in several different subtypes of B-cell lymphomas (Morin et al, 2011; Pasqualucci et al, 2011).
The awareness that ovarian cancer comprises several different subtypes with different molecular landscapes, the improved understanding of the genomics of these subtypes and the development of new active biologic agents hold the promise of improving ovarian cancer outcomes [10].
The most common form of malignant renal neoplasms is renal cell carcinoma (RCC), which is classified into several different subtypes based on the histomorphological features.
Analysis of gene expression arrays has resulted in the recognition of several fundamentally different subtypes of breast cancer [ 1].
On the other hand, several reports have demonstrated different subtypes of RET/PTC and different BRAF mutational statuses in individual PTC foci among patients with multifocal PTCs 7– 10.
However, a major practical advantage of the case-cohort studies is the ability to use the same subcohort for several outcomes such as different subtypes of disease [ 112].
Accordingly, research efforts have been focused on examining the effects of combinations of targeted therapy and immunotherapy in several different histological subtypes of cancer.
