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Amyotrophic lateral sclerosis (ALS) is a degenerative disease predominantly affecting motor neurons and manifesting as several different phenotypes.
We will discuss below how dumpy mutations with several different phenotypes could be found in a single exon.
Several different phenotypes produced by Wolbachia have been reported that promote its fitness; parthenogenesis of its host, male-killing, and cytoplasmic incompatibility (CI) (reviewed in [7]).
FastEpistasis is capable of analyzing several different phenotypes simultaneously, using the same genotypes.
Pleiotropy of common alleles is an expected feature of human diseases that have a major genetic component and manifests as an allele associated with several different phenotypes.
Furthermore, it is clearly evident that COPD is a heterogeneous disease characterized by several different phenotypes, distinguishable with respect to clinical presentation, frequency of exacerbations, pathophysiologic aspects, rate of lung function decline, radiologic imaging, and response to treatment [ 2].
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We have developed several different phenotype extraction methods to demonstrate the utility of the corpus, and tested these methods on a further corpus, i.e., ShARe/CLEF 2013.
There is now a growing realization that preeclampsia may be classified as a syndrome and that there may be several different preeclampsia phenotypes (such as mild, severe, early onset, late onset, maternal, placental, recurrent).
One is associated with several different obesity phenotypes in three independent datasets and is located within 153.5 155.5 Mb (–log(P) = 8.2 11.4) and the other reproduced the refined Bwtq1 QTL, showing significant effects on body weight and bone mineral content (–log(P) = 7.2).
In vitro studies have shown that the expression of Lewis antigens can phase vary at high frequencies (0.2 0.5%), which favors strain diversification and suggest that several different LPS phenotypes can exist in a bacterial population originating from a single cell [8].
Asthma is a heterogeneous airway inflammation which gives rise to several different clinical phenotypes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com