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The Toxin complexes (Tc's) are orally active insecticidal toxins, transformed both into transgenic plants [ 65] and most recently into recombinant termite gut bacteria [ 66] for insect control, which are encoded at several different genomic islands in Photorhabdus genomes.
let-7 miRNAs have been associated with the differentiated state in multiple other contexts [38], and consist of multiple family members located at several different genomic loci.
These large scale correlations were demonstrated with several different genomic elements, which were themselves identified and mapped through an assortment of different methods.
Probing with 'cox3' and 'rnl' also revealed multiple bands with varying intensity, again indicating that these mtDNA elements are present in several different genomic arrangements.
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To potentially overcome these limitations, Tox21 is investigating several different genomic-based platforms that would allow for the monitoring of gene expression patterns (signatures), induction or repression, (e.g., 200 1,000) in any cell type, including human primary and stem cells (undifferentiated and differentiated) in a 384-well plate format.
Most likely, the integrase of HPI-ICEEh1 is functional, because several different combinations of genomic islands and genomic modules were excised from the chromosome and formed circular structures, the integrase of EhGI1 was truncated, and EhGM3, EhGM4, and EhGM5 lack integrase genes.
Based on patterns of introgression, several different classes of genomic region in the hybridized genome have been identified.
These insulator bodies are thought to result from several insulators from different genomic locations coming together and looping the intervening chromatin fiber [14], [15], [37], [38], [39].
It has long been recognized that several different pathways of genomic instability exist.
Clonal heterogeneity is defined as the presence of several subclones possessing different genomic alterations within a tumor.
To test how well several assay types represent different genomic properties, we used published WGBS and RRBS data [ 112], the list of loci represented by the Illumina Infinium HumanMethylation450 microarray [ 110] and the HpaII loci represented by the HELP-tagging assay [ 108].
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